Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food or cosmetic.
Dermorphin 5mg
$89.95
Dermorphin 5mg
Dermorphin is a synthetic peptide, but it’s also a naturally occurring opioid peptide found in the skin of certain South American frogs, specifically those from the genus Phyllomedusa. It’s known for its potent analgesic (pain-relieving) effects due to its high affinity and selectivity for mu opioid receptors.
$89.95
Peptides will arrive in a lyophilized (powder) form for maximum stability
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Dermorphin
Dermorphin is an opioid peptide originally found in the skin of amphibians; it exhibits analgesic and antinociceptive activities, acting as an agonist at μ-opioid receptors (μORs). In animal models of thermal, mechanical, and chemical pain, dermorphin increases pain thresholds.
Product Info
Cas No. 77614-16-5
Purity ≥96%
Formula C40H50N8O10
Formula Wt. 802.88
Chemical Name
Tyrosyl-alanyl-phenylalanyl-glycyl-tyrosyl-prolyl-serinamide
IUPAC Name
(2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2- [[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl] amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl) propanoyl]pyrrolidine-2-carboxamide
Solubility Slightly soluble in water.
Appearance
White to off white powder
Shipping And Storage
Store Temp
-20°C
Ship Temp
Ambient
Refrences
Mizoguchi H, Bagetta G, Sakurada T, et al. Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine. Peptides. 2011 Feb;32(2):421-7. PMID: 21126548. Guzevatykh LS, Voronina TA, Emel’ianova TG, et al. Comparative analysis of analgesic activities of dermorphin, [DPro6]-dermorphin, and their C-terminal tripeptides. Izv Akad Nauk Ser Biol. 2007 Sep-Oct;(5):577-82. PMID: 18038625.